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JDRF has now rebranded to Breakthrough T1D.
Our name has changed, our mission has not.

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Breakthrough T1D takes next step in raising awareness of early detection, with support from Sanofi

We’re pleased to announce that we are launching a new initiative to raise awareness of the importance of early detection in type 1 diabetes (T1D), with support from Sanofi.
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Breakthrough T1D staff 20 August 2025

This announcement marks the beginning of a wider alliance of partners committed to helping every person who develops T1D begin their journey with the best possible support.

Reducing DKA

Early detection will reduce the number of diagnoses that occur during life-threatening diabetic ketoacidosis (DKA), offering a safer and more stable starting point for people who develop the condition. Knowing that you will develop symptomatic T1D in advance provides valuable time for people to learn how to manage the condition, explore treatment options and prepare both emotionally and practically.

A national screening programme by 2030

At the same time, type 1 diabetes is beginning to shift from a condition that can only be treated after symptoms appear to one that might be delayed. One therapy is currently awaiting regulatory approval, with many more in clinical trials

Early detection is opening the door to a future where living with T1D begins not in crisis, but with knowledge, preparation and support. Yet currently, there is no national early detection programme, and most people can only access screening through clinical studies. Our shared goal is to establish a comprehensive national screening programme by 2030.

Awareness of the signs and symptoms

As part of this programme of work, we’ll be developing a white paper on the benefits of early detection and a set of educational resources to help people understand how T1D develops. These materials will focus on the key signs and symptoms to look out for with a specific focus on the 4Ts which are tired, thirsty, thinner and going to the toilet more frequently. We’ll also provide guidance on how to access screening programmes and get tested once symptoms begin.

Karen Addington, CEO of Breakthrough T1D says: “Early detection of T1D offers something we’ve never had before – time to prepare, and options to act. Raising awareness. not only of screening but of signs and symptoms, is critical to ensure that more families can avoid the trauma of a diagnosis in crisis. Early detection provides a more hopeful beginning to life with T1D.”

We’re grateful for Sanofi’s support and look forward to welcoming more partners who share our commitment to changing what a T1D diagnosis looks and feels like, enabling earlier detection, better preparation and reducing the distress of emergency hospital visits.

Sanofi have provided financial support for raising awareness of the benefits of early detection of T1D but have no input or involvement into the content or output of our work.

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