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JDRF has now rebranded to Breakthrough T1D.
Our name has changed, our mission has not.

Our research

One day, we will create a world without type 1 diabetes. Until that day, your support is vital for our international research to cure, treat and prevent type 1.

A type 1 diabetes researcher working on a beta cells project, in the lab.

What research does Breakthrough T1D UK fund?

We fund international research that will cure, treat and prevent type 1 diabetes and its complications. We focus on investing in research that will transform the lives of people with type 1 diabetes – improving treatments today until we find a cure.

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400+

Over 400 active research studies are being funded by Breakthrough T1D UK around the world

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21

Breakthrough T1D UK-funded research is currently taking place in 21 countries

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20

At any one time, Breakthrough T1D UK is funding around 20 research projects in the UK

Learn about our research

Discover how we’re working to cure, treat and prevent type 1 diabetes

Recent research highlights

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A girl with type 1 diabetes after a teplizumab injection
Treatments

Teplizumab: The world’s first type 1 diabetes disease-modifying drug approved in the US

The US FDA recently approved a drug that can delay the onset of type 1 diabetes for up to three years, called teplizumab. This success wouldn’t have happened without 30 years of Breakthrough T1D UK funding research.

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Illustration of the hybrid closed loop technology system, funded as part of treatment research for type 1 diabetes by Breakthrough T1D UK.
Treatments

Hybrid closed loop to be recommended for over 100,000 people with type 1 diabetes

Since 2006, we have funded research to develop and test hybrid closed loop (HCL) technology, which links people's insulin pump to their continuous glucose monitor. Now, HCL is set to become available to many people on the NHS.

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Microscopic view of stem cells
Cure

Promising stem cell therapy for type 1 given green light to progress

For over 20 years, we funded Professor Doug Melton to grow stem cells into insulin-producing beta cells. Doug now works at Vertex Pharmaceuticals, who are running a clinical trial transplanting Doug’s lab-grown beta cells into people with type 1.

Latest research projects

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A photo of Dr Matthew Anson, a researcher funded by Breakthrough T1D and Novo Nordisk UK Research Foundation.
Treatment

Can hybrid closed loop technology affect eye problems in type 1 diabetes?

Dr Matthew Anson is studying whether hybrid closed loop technology, also known as an artificial pancreas, affects the worsening of diabetic eye disease.

Read more
A photo of researcher Dr Samet Sahin in his science lab.
Treatment

Engineering a device to measure how much insulin someone is making

Dr Samet Sahin is developing a simple tool to allow healthcare professionals to quickly and easily check someone’s C-peptide levels, a measure of how much insulin they are releasing.

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Treatment

Studying cells in the pancreas to help prevent low blood glucose in type 1 diabetes

Dr Thomas George Hill is studying a type of pancreatic islet cell, called a delta cell, which he thinks could be targeted with a treatment to help prevent low blood glucose in type 1 diabetes.

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A photo of Dr Rebecca Dewhurst-Trigg smiling and wearing a black top.
Prevention

Could islet helper cells in the pancreas delay or prevent type 1 diabetes?

Dr Rebecca Dewhurst-Trigg is investigating how supportive cells called mesenchymal stromal cells may help protect insulin-making beta cells from being destroyed in type 1 diabetes.

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A photo of Dr Richard Pulsford.
Treatment

Developing a simple tool to help people with type 1 diabetes exercise

Dr Richard Pulsford is developing a visual tool for people with type 1 diabetes that predicts the likelihood of their blood glucose going too low during exercise

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Parth Narendran
Prevention

Which drugs are best at protecting insulin-making beta cells?

Dr Parth Narendran is comparing how effective different treatments are for people newly diagnosed with type 1 diabetes at protecting their remaining insulin-making beta cells.

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An outdoor headshot of Dr Mandeep Marwah smiling and wearing a yellow coat.
Treatment

Developing a new type of dressing to improve diabetic wound healing

Dr Mandeep Kaur Marwah is developing a new type of dressing to help diabetic wounds heal more quickly.

Read more
Professor Yanick Crow
Prevention

Understanding the role of interferon in autoimmunity

Connect Immune Research has launched a first-of-its-kind research project to confront the UK’s high prevalence of autoimmune conditions.

Stories from the lab

Latest research news

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Dr Ana Cruz in her lab
Research
8 January 2025

Breakthrough in T1D treatment: Engineered islets produce insulin without immunosuppression

Sana Biotechnology, a US-based biotech company, has released clinical data showing that the first person receiving engineered islets from deceased donors is now producing insulin without the need for immunosuppressive drugs.

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Mum and daughter wearing Breakthrough T1D t-shirts and holding a flag in a park.
News
16 December 2024

Research and policy breakthroughs in 2024

Our highlights from a year full of breakthroughs in type 1 diabetes research and advocacy.

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Researcher with microscope
Research
13 December 2024

Breakthrough T1D funds four new type 1 diabetes research projects in the UK

We’ve awarded four new grants to UK researchers to help improve lives and develop cures for people living with type 1 diabetes.

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A photograph of two women. The woman on the right is a healthcare professional who has a hand on the other woman's arm.
Research
12 November 2024

New policy framework launches to improve sex and gender data in UK research

The framework aims to encourage UK researchers to consider different sexes (biological attributes) and genders (roles, behaviours and identity in society) to address gaps in health data.

Our research partnerships

We work with researchers and partner organisations to make sure we can improve life with type 1 diabetes as quickly as possible. Learn about the research we do in partnership with other organisations.

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Our research partnerships

Discover how we work with other organisations to help us make every penny we receive from our amazing supporters go even further to help people with type 1.

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Connect Immune Research

Learn about how we're partnering with other autoimmune research funders, pooling our resources to help prevent and cure a range of autoimmune conditions, including type 1 diabetes.

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A woman type 1 diabetes scientist in a laboratory

The Type 1 Diabetes Grand Challenge

The Type 1 Diabetes Grand Challenge is a partnership between the Steve Morgan Foundation, Diabetes UK and Breakthrough T1D UK. We are united by our ambition to cure type 1 diabetes.