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Our researchers are working on different ways to develop a cure for type 1 diabetes - from growing insulin-producing beta cells in labs to hacking the immune system.
Learn about the technologies that can deliver insulin automatically when needed. And discover the next generation of insulins that are currently being developed.
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Our volunteers generously give us their time, skills and experience to tell people about our work, and to help us raise vital funds for research into better treatments and ultimately a cure for T1D.
Our ambitious new roadmap is aimed at driving significant advancements in type 1 diabetes research, treatment, and care.
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Home > About Breakthrough T1D UK & our impact > Our research
One day, we will create a world without type 1 diabetes. Until that day, your support is vital for our international research to cure, treat and prevent type 1.
We fund international research that will cure, treat and prevent type 1 diabetes and its complications. We focus on investing in research that will transform the lives of people with type 1 diabetes – improving treatments today until we find a cure.
Over 400 active research studies are being funded by Breakthrough T1D UK around the world
Breakthrough T1D UK-funded research is currently taking place in 21 countries
At any one time, Breakthrough T1D UK is funding around 20 research projects in the UK
Discover how we’re working to cure, treat and prevent type 1 diabetes
Our researchers are working on lots of different ways to develop a cure for type 1 diabetes, from growing insulin-producing beta cells in labs to hacking the immune system to stop it attacking beta cells.
We’re improving lives by developing new ways to treat type 1 diabetes, until we find a cure. Our treatment research includes advancing technologies to help people with type 1 manage their blood glucose levels, creating new and improved types of insulin, and tackling diabetes complications.
Our prevention research aims to fix the problems with the immune system that lie at the heart of the condition. We’re also supporting screening projects to find people in the earliest stages of developing type 1 and delay their need for insulin injections.
The US FDA recently approved a drug that can delay the onset of type 1 diabetes for up to three years, called teplizumab. This success wouldn’t have happened without 30 years of Breakthrough T1D UK funding research.
Since 2006, we have funded research to develop and test hybrid closed loop (HCL) technology, which links people's insulin pump to their continuous glucose monitor. Now, HCL is set to become available to many people on the NHS.
For over 20 years, we funded Professor Doug Melton to grow stem cells into insulin-producing beta cells. Doug now works at Vertex Pharmaceuticals, who are running a clinical trial transplanting Doug’s lab-grown beta cells into people with type 1.
Dr Rachael Hughson-Gill is a researcher at the University of Lincoln, who is studying how body image issues affect young women with type 1 diabetes (T1D).
Dr Gordon Sloan and his team at the University of Sheffield are researching a new method to identify nerve pain (neuropathy) in teens and young adults with type 1 diabetes (T1D).
Dr Tom Wylie’s pioneering research project investigating the psychological impact of type 1 diabetes (T1D), in partnership with the Daphne Jackson Trust.
Dr Kathleen Gillespie and her team are researching how signalling molecules help coordinate immune cell attacks on the pancreas, contributing to T1D development.
Dr Kathleen Gillespie and her team will investigate whether existing tests could help predict how quickly a person in the early stages of T1D will progress.
Dr Matthew Anson is studying whether hybrid closed loop technology, also known as an artificial pancreas, affects the worsening of diabetic eye disease.
Dr Samet Sahin is developing a simple tool to allow healthcare professionals to quickly and easily check someone’s C-peptide levels, a measure of how much insulin they are releasing.
Dr Thomas George Hill is studying a type of pancreatic islet cell, called a delta cell, which he thinks could be targeted with a treatment to help prevent low blood glucose in type 1 diabetes.
Learn about clinical trials, how to get involved in the different kinds of type 1 diabetes research and view current opportunities.
Dr Rachel Besser, Consultant and Research Lead at Oxfordshire Children’s Diabetes Service, and researcher at the University of Oxford, on how teplizumab being approved in the US benefits children in the UK.
Globally, we have invested over £2 billion in research to date and are currently funding more than 400 research projects and 19 clinical trials. Breakthrough T1D UK has several funding opportunities available that address our mission to cure, treat and prevent type 1 diabetes.
A major UK study has shown that screening children for type 1 diabetes (T1D) can identify the condition in its earliest stages, before symptoms appear, offering families time, choices, and hope.
The European Commission has approved Teizeild, the European brand name for the immunotherapy teplizumab, for use in people with stage 2 type 1 diabetes (T1D). This marks an important step forward in efforts to delay the progression of the condition.
Highlights from an extraordinary year in type 1 diabetes (T1D) research, treatment, advocacy and policy.
These are the takeaways that matter most to our community from EASD, Europe’s biggest diabetes conference.
We work with researchers and partner organisations to make sure we can improve life with type 1 diabetes as quickly as possible. Learn about the research we do in partnership with other organisations.
Discover how we work with other organisations to help us make every penny we receive from our amazing supporters go even further to help people with type 1.
Learn about how we're partnering with other autoimmune research funders, pooling our resources to help prevent and cure a range of autoimmune conditions, including type 1 diabetes.
The Type 1 Diabetes Grand Challenge is a partnership between the Steve Morgan Foundation, Diabetes UK and Breakthrough T1D UK. We are united by our ambition to cure type 1 diabetes.
Don’t miss out on the latest research, inspiring stories, tech news, upcoming events, and handy information on living well with type 1. Join us now and receive it all straight to your inbox.
It’s thanks to your dedication that we have funded great progress in type 1 cure, treatment and prevention research. Help us to continue our vital research.
